Every month throughout our centenary year, we will be asking an IChemE member to write a blog about each of the centenary themes. The themes have been selected to highlight and celebrate the enormous contribution that chemical engineering has made to society over the last century.
IChemE member Elizabeth Cheeseman, who was part of the editorial panel looking at health, picks out her choices of elements to celebrate, communicate and inspire.
The UK Government Vaccine Taskforce (VTF) was established in April 2020 by the Government’s Chief Scientific Advisor, Sir Patrick Vallance, to drive forward, expedite and co-ordinate efforts to ensure that the UK population would have access to a clinically safe and effective vaccine against Covid-19.
Members of IChemE’s Covid-19 Response Team were approached to join the VTF to utilise their chemical, biochemical and process engineering expertise to enable delivery of the taskforce’s objectives.
We caught up one of the members, Vaughan Thomas, to find out more.
It was double celebrations for Micropore Technologies, who won in both the Innovative Product and Pharma categories at the IChemE Global Awards 2019 for their project Membrane Emulsification Finally Come of Age.
The team at Micropore Technologies have designed and developed a device (AXF-7), that will allow drugs with complex molecules to be delivered through a standard size needle and released in the body at a controlled rate, as well as making it easier for the patient to administer the drug themselves.
Find out more about the project in this video:
If you have a project demonstrating the best in process or technology in the pharmaceutical sector, why not enter the IChemE Global Awards 2020?
Addressing the need to generate new medicines and treatments for patients at a faster pace was something that UK consortium group – CPI, UCB Celltech, Lonza Pharma and Biotech, Horizon Discovery, Sphere Fluidics, and Alcyomics, have been developing over the past four years and earned them the IChemE Global Award 2019 in the Biotechnology Award category.
“If you involve chemical engineers earlier, you can get more manufacturable solutions earlier. It’s having that translational mindset in the project from an early stage, which makes a massive difference.”
The project incorporated various sectors of the biopharmaceutical industry together and working as team help advance the production and delivery of medication to patients more efficiently.
Picking up the Pharma Award at the IChemE Global Awards 2018 was a consortium group comprising of GSK, PM Group, Suncombe and ITT, for their project Fully Integrated Sterile Filtration Unit.
In this collaborative project, the team set out to find a lasting solution to manufacturing a life-saving drug using a sterile filtration system. The drug produced currently benefits 90,000 people every day and without this critical part of the function, patients would be without the medication they need.
Watch this video to find out more:
If you have a project demonstrating the best in process or technology in the pharmaceutical sector, why not enter the IChemE Global Awards 2019?
The theme this year for World Water Day is ‘Leave no one behind’, working to the Sustainable Development Goal of achieving universal access to safe and affordable drinking water by 2030. Playing a key role in this mission are chemical engineers from both academia and industry; who are working on water projects around the world.
In today’s blog we take a trip down memory lane, and reflect on some great examples of members who have used their chemical engineering skills to help people in developing countries access clean water.
Three researchers at the University of Birmingham are battling it out to be crowned the winner of the university’s Philanthropic Research Project 2018.
The university has announced the finalists of its research project competition – selecting three that have the potential to change lives. Birmingham has committed to fundraising for the chosen winner over the next year, helping to drive their research forward to potential commercialisation opportunities – ultimately providing benefit to more people.
One of the finalists is Dr Sophie Cox from the Department of Chemical Engineering. Her project, Engineering new medical systems to fight antimicrobial resistance, is focused on combating antibiotic resistance, which is predicted to kill more people than cancer in a few years’ time.
Read on to find out more about her project, and how you can help her chances of winning the competition.
Every year millions of people around the world die from vaccine preventable diseases. Why?
Well, researchers at the University of Bath, led by Dr Asel Sartbaeva found that keeping vaccines cold was the one of the biggest challenges in transporting these vital medicines around the world.
If the proteins in vaccines reach a temperature above 8ºC they can become ineffective and unusable – and in some cases, even toxic.
As a result, vaccination levels are 16% lower in low-income countries compared to the developed world, in part, because they do not have the electricity, infrastructure or equipment to store and transport these vital medicines.
To help tackle this challenge, Asel and her team have developed a method called ‘ensilication’ which involves encasing vaccines in silica to protect the proteins, and eliminate the need for refrigeration.
The technology has been several years in development, and as well as helping millions of people around the world, it is also highly sustainable. The material is non-toxic and biocompatible, and the elimination of refrigeration ultimately reduces the environmental burden of generating power to run medical fridges.
As Asel says: “It’s very important because today we don’t deliver vaccines to millions of people. In fact, statistically more than 7 million people die around the world from vaccine-preventable diseases.”
This amazing project won an IChemE Global Award in November 2017, under the category ‘Biotechnology’. Asel collected the Award from Peter Farrelly, Managing Director of PM Group – category sponsor.
Watch her reaction and find out more about the project in our short video:
Come back tomorrow when we’ll be shining the spotlight on another 2017 IChemE Global Award winner.
Are you feeling inspired to apply for the IChemE Global Awards 2018? Whether you would like to enter your own project, sponsor a category, or just attend to support your fellow professionals –register your interest here.
The IChemE Global Awards 2017 were held in Birmingham, UK on Thursday 2 November, held in partnership with Johnson Matthey and Wood.
It’s Friday, and the final stage of our IChemE Global Awards winners round-up. We hope you’ve enjoyed the posts this week, and learnt a little more about each of our winners.
Today we are shining a light on the research superstars of the Awards. IChemE has always maintained strong ties with the academic community, supporting the host of ChemEngDayUK each year and accrediting courses. We also do proactive work with our UK Research Committee, who last night launched ten chemical engineering research case studies that have had a significant impact on the UK economy. Read all about the research event, held in Parliament, here.
So, on to the winners and the final three IChemE Global Awards videos, produced in association with Morgan Sindall. All these winners have demonstrated fantastic research capability, but most importantly their studies have a real-world application that can really make a difference.
Enjoy these final three videos, and season’s greetings to all our members worldwide.
Thanks for joining us for round two of our blog series, celebrating the very worthy winners of the IChemE Global Awards 2016. With help from our friends at Morgan Sindall we have produced a video for every category, and each one includes a special interview with the winners.
Yesterday we looked at some life-changing products, and the theme remains the same in today’s post. However today’s products have a little something extra – they have been specially designed to help tackle a problem in low-middle income countries.
This goes to show that chemical engineering really does matter, and that the work of chemical engineers doesn’t just make our lives easier – it is solving some of the world’s biggest poverty issues.
Enjoy the three videos below, and stay tuned the rest of the week when we reveal even more winning projects.
To help you stay up-to-date with the latest achievements from the chemical engineering research community here is our monthly instalment with some of the latest stories.
September’s five stories of amazing chemical engineering research and innovation are:
The Popeye effect – powered by spinach
Popeye was right; we can be powered by spinach! Researchers from the Technion-Israel Institute of Technology have developed a bio-photo-electro-chemical (BPEC) cell that produces electricity and hydrogen from water using sunlight, using a simple membrane extract from spinach leaves. The article, publish in the journal Nature Communications, demonstrates the unique combination of a man-made BPEC cell and plant membranes, which absorb sunlight and convert it into a flow of electrons highly efficiently. The team hope that this paves the way for the development of new technologies for the creation of clean fuels from renewable sources. The raw material of the device is water, and its products are electric current, hydrogen and oxygen.
To help you stay up-to-date with the latest achievements from the chemical engineering research community here is our monthly installment with some of the latest stories.
Here are five stories of amazing chemical engineering research and innovation:
Making dirty water drinkable Engineers from Washington University in St. Louis have found a way to use graphene oxide sheets to transform dirty water into drinking water. “We hope that for countries where there is ample sunlight, such as India, you’ll be able to take some dirty water, evaporate it using our material, and collect fresh water,” said Srikanth Singamaneni, associate professor of mechanical engineering and materials science.
The new approach combines bacteria-produced cellulose and graphene oxide to form a bi-layered biofoam. “The properties of this foam material that we synthesized has characteristics that enhances solar energy harvesting. Thus, it is more effective in cleaning up water,” said Pratim Biswas, the Lucy and Stanley Lopata Professor and chair of the Department of Energy, Environmental and Chemical Engineering.
On 24 May 2016 at the Edinburgh International Conference Centre, Professor Jonathan Seville was inaugurated as IChemE President for 2016-17. The Executive Dean of Engineering at University of Surrey delivered his Presidential Address on the subject of relevance. Jonathan challenged us all to think: how will the Institution and the profession stay relevant in a world that is rapidly changing?
Since the end of ChemEng365 our ChemEngBlog has become a little quiet. To make sure you stay up-to-date with the latest achievements from the chemical engineering research community we will be providing you with monthly updates on some of the latest stories.
So here are five stories of amazing chemical engineering research and innovation:
Seven chemical separations to change the world
David Sholl and Ryan Lively, chemical and biomolecular engineers, from the Georgia Institute of Technology, US, highlighted seven chemical separation processes that, if improved, would reap great global benefits. The list they have drawn up is not exhaustive (we are sure there are more we could add!) but includes; hydrocarbons from crude oil, uranium from seawater, alkenes from alkanes, greenhouse gases from dilute emissions, rare-earth metals from ores, benzene derivatives from each other, and trace contaminants from water.
IChemE’s Special Interest Groups (SIGs) are an essential way for our members to share knowledge and collaborate on initiatives, which are of significance to their sector.
Today is World Water Day, and our Water SIG is a hugely important part of providing expert advice and consultation to the innovations that could change our world. Water is essential to life, it must be sustainable or we cannot survive. Chemical engineers are an important part of making sure water provision is sufficient, clean, economical, and environmentally-friendly.
Chris Short, Chair of the IChemE Water SIG, explores in more detail the current challenges for the water sector in today’s blog post. Read on to hear his thoughts, and feel free to join the conversation on Twitter using #WorldWaterDay or by leaving a comment below:
Name: Chris Short Job: Consultant and Chartered Chemical Engineer Company: Chris Short Water Quality (previously Yorkshire Water) Special Interest Group: Water, Chairman
Today is World Water Day, and I’ll be attending a conference in Leeds, UK, on Innovations in Wastewater Treatment. The focus will be on the recovery of value from wastewater and I expect to hear how leading-edge technologies are performing and what new processes are being evaluated by researchers.
Over the last few years, cycling has seen a meteoric rise in both popularity and participation. Its most gruelling and testing competition, the Tour De France, drew to a close last month with another British victory.
So it seems quite apt to share how chemical engineering plays a part in this sport.
The phrase ‘chemical engineering in cycling’ may raise a few eyebrows. Indeed, some of the ways in which competitors have broken the rules can be – if you’re able to discount the morality of the outcome – seen as impressive feats of human engineering.
I’m sure you’ve heard of blood doping, where athletes improve their aerobic capacity and endurance through either one of the two following ways:
The ChemEng365 campaign concluded at the end of May when Geoff’s term as president ended. But of course, all the amazing chemical engineering research and innovation still goes on. So, it seems only fitting to give you a research round-up on all things chemical and process engineering for the month of June – just in case you missed anything!
Injectable hydrogel could help wounds heal more quickly
Chemical engineering has to be one of the most creative of all professions. We look for opportunities in everything, even in the air that surrounds us.
In the early 20th century, Carl von Linde pioneered the process of air separation, splitting air into its pure components. He developed a technique to obtain pure oxygen and nitrogen by means of fractional distillation from liquefied air.
Since then, air separation has been applied to many products we use every day. In February, I attended an IChemE event at the University of Surrey. During the event, I met Jama Salimov, an Advanced Process Control Engineer at Air Products. Jama was keen to shine a light on his work in air separation and ensure that we all understand its many applications.
Liquid Nitrogen
Air separation typically separates air into its primary components – nitrogen and oxygen. However, it can also isolate some of the more rare parts of the air such as argon.
The products of air separation have a wide variety of uses in our everyday lives. Many of us use them without even realising it – and Jama was keen to tell me all about them.
The World Health Organization (WHO) reports that as many as 2.5 billion people around the world do not have access to adequate toilet facilities.
Poor sanitation results in contaminated drinking water and the spread of infectious diseases including Cholera and Dysentery, which cause severe diarrhoea, dehydration and if left untreated, death (see my blog, ‘Everyone should have a human right to water’).
Every year, around 1.5 million people – mostly children under five years old – die from diarrhoea. Drastic action is needed in order to make safe sanitation accessible to all.
Only last week, I observed that we sometimes have a tendency to take things for granted in the developed world. My blog, ‘Chemical engineer develops sanitary towels to help girls stay in school’ was well received and has prompted me to look at some other work by chemical engineers who are making a difference in the developing world.
Chemotherapy is a type of cancer treatment that uses one or more chemical substances to kill cancerous cells. It can be used in conjunction with other cancer treatments, or given alone. But as there are over 100 different chemotherapy drugs, our ability to prescribe the most effective drug to treat a particular tumour can be difficult.
Picture Credit | MIT MIT chemical engineers have designed an implantable device that can deliver many drugs at once, allowing researchers to determine which drugs are the most effective against a patient’s tumor.
The device, which is about the same size as a grain of rice, is not swallowed or injected, but instead is implanted directly into a cancerous tumour, where it can directly administer small doses of up to 30 different drugs.
Maple syrup can render bacteria more vulnerable to antibiotics.
The syrup, which is produced by concentrating the sap from North American maple trees, is a rich source of phenolic compounds with antioxidant properties.
And it is these antioxidant properties that prompted the team, led by Professor Nathalie Tufenkji, investigate the potential of maple syrup.
The team began by removing a concentrated extract from the syrup. They tested this extract on several infection-causing strains of bacteria, including E. coli and Proteus mirabilis (a common cause of urinary tract infection).
The syrup was mildly effective combating the bacteria on its own. However, once mixed with the antibiotics the maple syrup was particularly effective; seemingly synchronising its assault with the pharmaceutical ingredient.
Here in the UK and other developed countries, it’s all too easy to take some things for granted, such as access to education, to clean water and to sanitary facilities.
When we look at the developing world, it can be difficult to comprehend the challenges people face on a daily basis.
Photo Credit | Anton_Ivanov / Shutterstock.com
In Ethiopia, as many as 18 million young girls and women have no access to sanitary towels. This forces many young girls to drop out of school. But the good news is that one chemical engineer is trying to change that.
For most girls, their first menstrual cycle is awkward and embarrassing, but seen as a natural transition towards womanhood. However, in Ethiopia it can be an incredibly taboo subject. As a consequence, misinformation, negative beliefs and myths hold sway.
In the rural Tigray region of Ethiopia, where chemical engineer Freweini Mebrahtu grew up, young girls found out about their menstrual cycle through overheard rumour and myth; often leaving them shocked, confused and afraid.
Very few discoveries truly revolutionise the way we look at the world.
However, the discovery of the structure of DNA is one of them. And it was on this day in 1953, that the structure of DNA was published in the journal Nature.
This discovery is often seen as controversial, not due to its scientific content, but the fact that the work was largely attributed to one team; Watson and Crick.
This work was published at the same time in a number of papers in Nature by three teams: Watson and Crick; Wilkins, Stokes, and Wilson; and Franklin and Gosling.
The key break through for Watson and Crick’s work came from Rosalind Franklin who studied DNA using X-ray crystallography, but this was largely unacknowledged at the time. In 1962 Crick and Watson, along with Wilkins, received a Nobel Prize for their discovery. Rosalind had died four years earlier so was not eligible for a Nobel Prize.
So to ensure that we celebrate all their work today, I thought I would bring to your attention a recent innovation, which would not have been possible without this major discovery.
The team used synthetically designed shape-shifting molecules which are able to resemble natural DNA bases, but can convert into a different molecular structure by repositioning their hydrogen atoms on nitrogen and oxygen atoms.
Now that we are in the home stretch of my presidency, I thought I’d look a little closer to home for examples of chemical engineering success. IChemE’s Corporate Partners are a great place to start.
AstraZeneca, a multinational pharmaceutical company employing around 57,000 people worldwide, were awarded Silver Corporate Partner status in 2011.
They are one of only a handful of companies involved in every aspect of pharmaceutical production from start to finish; from research to supply. So next time you pick up a prescription, there’s a good chance that AstraZeneca might have been involved.
One of their latest drugs to be approved is Lynparza, which is prescribed to patients who have been diagnosed with a mutated form of ovarian cancer.
Over 7,000 women in the UK are diagnosed with ovarian cancer every year. It’s the fifth most common cancer among women, mainly affecting the over 50’s – although it can affect women of any age.
Skin cancer is amongst the most common forms of cancers in the world with its highest incidence in Australia, New Zealand, the US and Europe.
The World Health Organisation (WHO) estimates that between two to three million non-melanoma and 132,000 melanoma skin cancers are diagnosed each year.
Photo Credit | Queen’s University Belfast Dr David Hazafy
The team, led by Dr David Hazafy, have developed a strip of plastic – containing ‘smart’ ink – which turns colourless from an initial blue colour to indicate a high exposure of ultraviolet light from the sun. This should prompt the user to move into the shade before burning, reducing the risk of skin cancer.
Spinal cord injuries are extremely serious and the road to recovery is often a long one.
Two million people worldwide are affected by spinal cord problems that result in the loss of motor and sensory function below the point of injury, which can be devastating.
I’ve blogged previously about a team from Stanford University, which is working reduce the trauma of injections and improve the ‘healing help for spinal injuries‘. It’s an area where chemical engineers are making a difference. Here’s another great example.
Her goal is to develop an injectable material with the potential to provide biochemical and physical guidance for regenerating nerves across an injury site.
Being a part of the blogosphere over the past 307 days has opened my eyes to how many of us bloggers are actually out there. So I was especially pleased to read today’s story about how blogging caused a scientific breakthrough.
Research into the innate immunity of opossums (marsupials found in the Americas) to a variety of snake venoms and their possible use to create antivenoms was first patented by Binie Ver Lipps in 1996.
Photo Credit | San Jose State University Dr Claire Komives
However, this research went largely unnoticed. But Binie’s work was mentioned by a blogger in 2012. This led to an article being written on Yahoo!News, which was subsequently read by chemical engineering professor Dr Claire F. Komives.
Inspired by the story Claire and her team, from San Jose State University, US, demonstrated that genetically modified bacteria could produce the protective peptide at low costs.
This simple peptide could prevent countless deaths from snakebites and the antivenom relies on a sequence of just 11 amino acids, copied from an opossum protein.
When someone suffers a serious injury, timing can literally be a matter of life or death. Blood loss must be tackled immediately, but care must also be taken to prevent infection of the wound.
The group developing these smart bandages is led by Professor Paula T. Hammond, the David H. Koch Chair Professor of Engineering in the Chemical Engineering Department at MIT. Paula suggests that the bandages might prove particularly effective in the treatment of wounded soldiers on the battlefield when a medic is not present.
When I read through scientific journals, the articles that grab my attention aren’t always the ones describing the most novel ideas. Sometimes it’s enough to just make something easier. That’s why today’s story appealed to me.
Many everyday products including medicines, beauty products and foodstuffs contain emulsions: liquids with tiny droplets of another liquid suspended within them (see my blog ‘food, glorious, food…emulsions‘). A classic example that we all can create at home is vinaigrette (salad dressing), which is an emulsion of oil and vinegar.
Photo Credit | Christine Daniloff\MIT MIT researchers designed these complex emulsions to change their configuration in response to stimuli, such as light, or the addition of a chemical surfactant.
Vinaigrette is a straightforward two component mixture. However, things get far more interesting when you suspend a liquid within a liquid, within a liquid. These complex emulsions (in this case a double emulsion) can be tailored for use in specific applications.
I’ve talked a good deal in recent posts about novel methods of drug delivery and vaccination (see ‘Making our bodies accept drugs faster’ and ‘Injecting from the instead’) however, today’s blog is about a product that is a step closer to being adopted world-wide.
Marks’s Nanopatch™ idea was to offer a needle-free method of drug delivery that could be widely used and increase vaccine efficacy.
In 2011 UniQuest, the University of Queensland’s commercialisation company, helped Mark found Vaxxas to advance the possibility of Nanopatch™ becoming a clinically-proven product.
Today, Vaxxas and Mark are getting closer to making that idea a reality by raising £12.7 million of funding for a series of clinical programs and the development of a pipeline of new vaccine products for major diseases.
In recent years we have seen increasing interest in new approaches to drug delivery with greater focus on the efficiency and flexibility of the drugs we use.
Today, I want to highlight a different approach; the use of implants as drug delivery devices. Implants offer several advantages over pills or injections, but often result in immune responses that hinder their performance.
A group of researchers from the Indian Institute of Science (IISc), in Bangalore, India, have developed a biodegradable polymer that acts as an anti-inflammatory agent and allows better acceptance of bio medical implants in the human body.
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